Anthocephalus Cadamba extract may destroy cancer cells, according to a multi-institutional research. The synergistic actuation of Reactive Oxygen Species (ROS) intervened autophagy by light activated nanoliposomes can be a helpful system for upgrading the anti cancer capability of combinational treatments, says the research drove by scientists from the Indian Institute of Technology (IIT), Hyderabad.
The research includes Department of Biomedical Engineering, IIT, Hyderabad, Department of Biotechnology and Bioinformatics, University of Hyderabad, Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay and Division of Molecular Medicine, Bose Institute, Kolkata.
Aravind Kumar Rengan at Department of Biomedical Engineering, IIT Hyderabad said, “We have taken organic solvent mediator extract from plant Anthocephalus Cadamba and then tested this extract on various cell lines, both normal healthy cell lines and cancer cell lines. We found that this extract from this plant is very selective in killing cancer cells.”
Done as a component of the PhD work of the understudies, the research has been as of late distributed in logical diary Nanoscale. The scientists did High Performance Liquid Chromatography (HPLC) and discovered some components, two of them not announced before. The group completed some essential in-vitro research with cell lines in lab-level conditions.
“There are many compounds which show very good results in in-vitro and animal studies but they fail in clinical trials,” Rengan added. “Unless and until we test and do stage-I clinical trials we are not very sure how effective it will be in human system.”